She made her cinematic debut with Rehnaa Hai Terre Dil Mein opposite R. Madhavan. The film was not a box office success. A series of unsuccessful films followed, among them Tumsa Nahin Dekha and Deewaanapan.
In 2005, Mirza appeared in Parineeta, a Vidhu Vinod Chopra production. She also played in the music video Kajara Mohabbat Wala alongside Sonu Nigam from the album Kajara Nite. The album contained multiple remixes, but was mainly advertised with the title song, sang by Sonu Nigam and Alisha Chinai.
She has also appeared in Dus and in Fight Club. She will appear later this year in Familywala and Naa Naa Karte.Early in her career she was tagged as a look-alike of Aishwaraya Rai.
